| 发明名称 |
HLA-E Binding |
| 摘要 |
The invention relates to a method of causing an interaction of CD94/NKG2+ cells, which method comprises contacting the cells with recombinant HLA-E under binding conditions. The HLA-E property of binding to CD94/NKG2 receptors on NK cells and a subset of CD8+ T cells is useful for targeting CD94/NKG2+ cells for a variety of purposes such as identification, isolation, killing or inactivation. |
| 申请公布号 |
EP2144065(A1) |
申请公布日期 |
2010.01.13 |
| 申请号 |
EP20090165917 |
申请日期 |
1998.12.04 |
| 申请人 |
ISIS INNOVATION LIMITED |
发明人 |
BRAUD, VERONIQUE;ALLAN, DAVID;OGG, GRAHAM;O'CALLAGHAN, CHRISTOPHER;MCMICHAEL, ANDREW |
| 分类号 |
A01K67/027;G01N33/569;A61K35/12;A61P35/02;A61P37/06;C12N5/10;C12N15/09;C12Q1/04;G01N33/53;G01N33/566 |
主分类号 |
A01K67/027 |
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