摘要 |
<p>The present invention provides means and methods for risk assessment and/or diagnosis and/or prognosis of obesity and/or type II diabetes in humans, based on the detection of nucleic acid biomarkers belonging to, or associated with, a set of SNPs in the fatso ( FTO ) gene. The present invention also provides means and methods for identifying a SNP haplotype associated with obesity and/or type II diabetes susceptibility in humans, for selecting pharmaceutical agents useful in prevention and/or treatment of obesity and/or type II diabetes in humans, for haplotyping the fatso ( FTO ) gene in humans.</p> |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2;INSTITUT PASTEUR DE LILLE |
发明人 |
DINA, CHRISTIAN, RAFAEL;GALLINA DELAMARE, SOPHIE, CATHERINE;CHEVRE, JEAN-CLAUDE;MEYRE, DAVID, JEAN-CLAUDE;FROGUEL, PHILIPPE |