DERIVATIVES OF N-[PHENYL(PIPERIDIN-2-YL) METHYL] BENZAMIDE, THE PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS

摘要

The invention relates to compounds having general formula (I), (see formula I) wherein - A denotes: a group with formula N-R1 in which R1 denotes a hydrogen atom, an alkyl group, a cycloalkyl group, a phenylalkyl group, an alkenyl group or an alkynyl group; or a group with formula N+ (O-) R1 in which R1 is as defined above; or a group with formula N+ (R) R1 in which R denotes an alkyl group and R1 is as defined above. X denotes a hydrogen atom or one or more substituents selected from the halogen atoms and the trifluoromethyl, alkyl and alkoxy groups. - R2 denotes a hydrogen atom, one or more substituents selected from the halogen atoms and the trifluoromethyl, alkyl, alkoxy, amino groups with formula NR3R4 in which R3 and R4 each denote a hydrogen atom or an alkyl group or, together with the nitrogen atom bearing same, form a pyrrolidine, piperidine or morpholine ring, or an optionally substituted phenyl group. The invention is suitable for use in therapeutics.