摘要 |
The present invention relates to compounds of formulae (I) and (II) (see formula I) (see formula II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-one s, 4- hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R10 an d R20 taken together are formulae (III) and (IV). (see formula III) (see formula IV)
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申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
STROHBACH, JOSEPH WALTER;MORRIS, JOEL;ARISTOFF, PAUL ADRIAN;THAISRIVONGS, SUVIT;ANDERSON, DAVID JOHN;JOHNSON, PAUL D.;SKULNICK, HARVEY IRVING;SCHWARTZ, THERESA M.;SKALETZKY, LOUIS L.;BUNDY, GORDON L.;TOMMASI, RUBEN A.;GAMMILL, RONALD B.;ROMINES, KAREN RENE;TURNER, STEVEN RONALD;LUKE, GEORGE P. |