发明名称 Z-STYRYL SULFONE ANTICANCER AGENTS
摘要 (Z)-styryl benzylsulfones of formula (I) are useful as anticancer agents: wherein R1 is selected from the group consisting of hydrogen, chloro and nitro; R2 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, chloro, bromo, iodo and fluoro; and R3 and R4 are independently selected from the group consisting of hydrogen, lower akyl, nitro, chloro, bromo, iodo and fluoro; provided that at least one of R1 or R2 is hydrogen. The corresponding (Z)-styryl benzylsulfides are useful as intermediates in the preparation of the biologically active (Z)-styryl benzyl sulfones.
申请公布号 CA2368653(C) 申请公布日期 2010.01.12
申请号 CA20002368653 申请日期 2000.03.30
申请人 TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 发明人 REDDY, E. PREMKUMAR;REDDY, M. V. RAMANA
分类号 A61P35/00;C07C317/10;A61K31/10;C07C317/18;C07C321/20;C07C323/07 主分类号 A61P35/00
代理机构 代理人
主权项
地址
您可能感兴趣的专利