| 发明名称 |
SILENCING AND RIG-1 ACTIVATION BY DUAL FUNCTION OLIGONUCLEOTIDES |
| 摘要 |
<p>The invention describes a method of determining whether a double stranded RNA (dsRNA) silences gene expression in a cell in vivo by an RNA interference (RNAi) mechanism by performing 5'- rapid amplification of cDNA ends (5'RACE) to detect the cleavage site of the mRNA in the RNA sample.</p> |
| 申请公布号 |
WO2010002851(A1) |
申请公布日期 |
2010.01.07 |
| 申请号 |
WO2009US49194 |
申请日期 |
2009.06.30 |
| 申请人 |
HARTMANN, GUNTHER;ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
HARTMANN, GUNTHER |
| 分类号 |
A61K31/7088;C12Q1/68;C07H21/00;C12N15/11 |
主分类号 |
A61K31/7088 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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