发明名称 |
NAPHTHYRIDININONES AS AURORA KINASE INHIBITORS |
摘要 |
Naphthyridinone derivative compounds that inhibit Aurora kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed Aurora kinases such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases. |
申请公布号 |
CA2727103(A1) |
申请公布日期 |
2010.01.07 |
申请号 |
CA20092727103 |
申请日期 |
2009.06.29 |
申请人 |
MERCK PATENT GMBH |
发明人 |
XIAO, YUFANG;CHEN, XIAOLING;KARRA, SRINIVASA R.;HUCK, BAYARD R.;SUTTON, AMANDA E.;GOUTOPOULOS, ANDREAS |
分类号 |
C07D471/04;A61K31/436;A61P35/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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