发明名称 COMBINATION COMPRISING A MEK INHIBITOR AND AN AURORA KINASE INHIBITOR 188
摘要 The present invention relates to a therapeutic combination comprising a MEK inhibitor and an Aurora kinase inhibitor, and to methods for the production of an anti-cancer effect in a patient, which is accordingly useful in the treatment of cancer in a patient. More specifically the present invention relates to: a therapeutic combination comprising a MEK inhibitor and an Aurora kinase inhibitor; a combination product comprising a MEK inhibitor and an Aurora kinase inhibitor, a kit of parts comprising a MEK inhibitor and an Aurora kinase inhibitor; use of a therapeutic combination, combination product or kit of parts in the treatment of cancer; a method of treating cancer comprising administering the therapeutic combination, combination product or kit of parts to a patient. The therapeutic combination and methods of the invention are also useful in the treatment of conditions in which the inhibition of MEK and/or Aurora kinase is beneficial.
申请公布号 US2010004247(A1) 申请公布日期 2010.01.07
申请号 US20080332068 申请日期 2008.12.10
申请人 ASTRAZENECA AB 发明人 MUNDT KIRSTEN ELISABETH;SMITH PAUL DAVID
分类号 A61K31/50;A61K31/4184;A61P35/00 主分类号 A61K31/50
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