| 发明名称 |
SPECIFIC KINASE INHIBITORS |
| 摘要 |
Resorcylic acid lactones having a C5-C6 cis double bond and a ketone at C7 and other compounds capable of Michael adduct formation are potent and stable inhibitors of a subset of protein kinases having a specific cysteine residue in the ATP binding site.
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| 申请公布号 |
US2010004234(A1) |
申请公布日期 |
2010.01.07 |
| 申请号 |
US20090536884 |
申请日期 |
2009.08.06 |
| 申请人 |
KOSAN BIOSCIENCES INCORPORATED |
发明人 |
SANTI DANIEL V.;REID RALPH C.;HUTCHINSON C. RICHARD;SUNDERMANN KURT F.;LAU JANICE |
| 分类号 |
A61K31/365;A61K31/4523;A61K31/496;A61K31/5377;A61P35/00;C07D493/04;C12N5/00 |
主分类号 |
A61K31/365 |
| 代理机构 |
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代理人 |
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| 主权项 |
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