METHODS OF USE OF ADENINE DERIVATIVES FOR THE TREATMENT OF DIABETES AND OTHER DISORDERS

摘要

This invention provides methods for the prevention and treatment of glucose- associated diseases such as diabetes using adenine derivatives having the formula: or pharmaceutically acceptable salts, hydrates, solvates, tautomers, or optical isomers thereof, wherein the variables are as defined herein. Also provided for this purpose are pharmaceutical compositions, kits and articles of manufacture comprising such compounds.