发明名称 |
NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, USE OF THE CATECHOL DERIVATIVE, AND USE OF THE PHARMACEUTICAL COMPOSITION |
摘要 |
Disclosed are a compound represented by general formula (I) (wherein R1 and R2 each represents a hydrogen, a lower acyl, a lower alkoxycarbonyl or the like; R3 represents a lower alkyl, a halogenated lower alkyl, a cycloalkyl, a heterocycloalkyl, an optionally substituted aryl, an optionally substituted heteroaryl or the like; and R4 represents a cyano, a lower alkoxycarbonyl, a carboxy or the like) having a strong COMT inhibitory activity or a pharmacologically acceptable salt thereof, a pharmaceutical composition containing the compound or a salt thereof, and uses of the compound, the salt and the composition.
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申请公布号 |
CA2729405(A1) |
申请公布日期 |
2010.01.07 |
申请号 |
CA20092729405 |
申请日期 |
2009.06.26 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIKAWA, TAKEHIRO;KOBAYASHI, SATOKO;INOUE, HITOSHI;UENO, YASUNORI;YOSHIDA, MASAKO;TANAKA, NOBUYUKI |
分类号 |
C07C205/61;A61K31/192;A61K31/24;A61K31/277;A61K31/351;A61K31/381;A61K31/40;A61K31/42;A61K31/425;A61K31/4453;A61K31/495;A61K31/5375;A61K31/55;A61P9/12;A61P25/16;A61P25/24;A61P43/00;C07C255/56;C07C255/57;C07D261/08;C07D277/24;C07D295/10;C07D309/06;C07D333/22 |
主分类号 |
C07C205/61 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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