摘要 |
Disclosed herein are compositions comprising 5-aminosalicylic acid (5-ASA), or a pharmaceutically acceptable salt thereof and an antioxidant, or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods of treating an inflammatory bowel disease in a subject, reducing cytokine gene expression in colonic tissue of a subject, and reducing myeloperoxide activity in colonic tissue of a subject, comprising administering to the subject a therapeutically-effective amount of a composition comprising 5-ASA, or a pharmaceutically-acceptable salt thereof, and an antioxidant, or a pharmaceutically acceptable salt thereof.
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