发明名称 |
FORMULATIONS OF 5-FLUOROCYTOSINE AND USES THEREOF |
摘要 |
The disclosure provides an extended release formulation of 5- f luorocytosine. In another aspect, a method of treating a fungal disease is provided. The method comprises administering to a subject in need thereof a fungus-treating effective amount of a composition comprising 5-f luorocytosine. In yet another aspect, a method of treating a cancer is provided. The method comprises administering to a subject in need thereof a sufficient amount of an expression vector to induce expression of cytosine deaminase which is capable of converting 5-f luorocytosine to 5-f luorourcail in cells of the cancer and a cancer-treating effective amount of a composition comprising 5-f luorocytosine. |
申请公布号 |
CA2724740(A1) |
申请公布日期 |
2010.01.07 |
申请号 |
CA20092724740 |
申请日期 |
2009.06.30 |
申请人 |
TOCAGEN INC. |
发明人 |
GRUBER, HARRY E.;JOLLY, DOUGLAS;OLMSTEAD, KAY |
分类号 |
A01N43/04;A61K31/70 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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