COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING PYRIDAZINE DERIVATIVES
摘要
The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Table 1 or encompassed by formula I) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
申请公布号
WO2009131947(A3)
申请公布日期
2010.01.07
申请号
WO2009US41145
申请日期
2009.04.20
申请人
INSTITUTE FOR ONEWORLD HEALTH;RUSSELL, MICHAEL, GEOFFREY NEIL;DOYLE, KEVIN, JAMES;PEACH, JOANNE