<p>The invention relates to diazo bicyclic mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.</p>
申请公布号
EP2139490(A2)
申请公布日期
2010.01.06
申请号
EP20080745750
申请日期
2008.04.14
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人
WANG, SHAOMENG;PENG, YUEFENG;SUN, HAIYING;CAI, QIAN;NIKOLOVSKA-COLESKA, ZANETA;LU, JIANFENG;QIU, SU