GLUCOSAMINE DISACCHARIDES, METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND THEIR USE

摘要

The invention relates to .beta.(16) glucosamine disaccharides having general formula (I) to a method for preparing these disaccharides, comprising the steps of: i) providing a starting material comprising lipid A moiety of lipopolysaccharide-comprising microorganisms; and ii) subjecting the startin g material to an alkaline treatment such that lipid A moiety is O-deacylated a t the 3-position and at the 3'-position, to pharmaceutical compositions comprising as an active ingredient these disaccharides, and to these disaccharides for use as an immunomodulating agent, anti-tumor agent, and vaccine component.