| 发明名称 |
BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS |
| 摘要 |
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I: A particular embodiment is
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| 申请公布号 |
US2009324569(A1) |
申请公布日期 |
2009.12.31 |
| 申请号 |
US20080275163 |
申请日期 |
2008.11.20 |
| 申请人 |
DECODE GENETICS EHF |
发明人 |
SINGH JASBIR;GURNEY MARK E.;BURGIN ALEX;SANDANAYAKA VINCENT;KISELYOV ALEXANDER;MOTTA ADALIE;SCHILTZ GARY;HATEGAN GEORGETA;HAGEN TIMOTHY |
| 分类号 |
A61K31/44;A61K31/122;A61K31/415;A61K31/4164;A61K31/4245;A61K31/435;A61K31/437;A61K31/4412;A61K31/4427;A61K31/4439;A61K31/445;A61K31/506;A61K31/5377;A61K31/54;A61P9/00;A61P11/00;A61P35/00;C07D213/72;C07D231/12;C07D237/14;C07D277/38;C07D285/135;C07D401/04;C07D401/06;C07D403/10;C07D413/06 |
主分类号 |
A61K31/44 |
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