发明名称 |
MITOCHONDRIAL-NUCLEAR EXCHANGED CELLS, TISSUES, ORGANS AND ANIMALS |
摘要 |
Provided herein are mitochondrial-nuclear exchanged cells and animals comprising mitochondrial DNA (mtDNA) from one subject and nuclear DNA (nDNA) from a different subject. Methods for producing a mitochondrial-nuclear exchanged animal and animals made by the methods are provided. Also provided are methods of screening for agents useful for treating a disease or disorder using mitochondrial-nuclear exchanged animals or cells, tissues or organs thereof.
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申请公布号 |
US2009328241(A1) |
申请公布日期 |
2009.12.31 |
申请号 |
US20090486375 |
申请日期 |
2009.06.17 |
申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
BALLINGER SCOTT WEBSTER;WELCH DANNY R.;KESTERSON ROBERT ALLEN;JOHNSON LARRY W. |
分类号 |
G01N33/00;A01K67/00;C12N5/00;C12N15/00;C12Q1/02 |
主分类号 |
G01N33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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