发明名称 |
Preparation of pharmaceutical formulations |
摘要 |
A process for the production of a composition comprising a water-insoluble opioid which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble opioid, ii) a water soluble carrier, and iii) a solvent for each of the opioid and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the opioid in the carrier
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申请公布号 |
US2009325995(A1) |
申请公布日期 |
2009.12.31 |
申请号 |
US20070309341 |
申请日期 |
2007.07.13 |
申请人 |
DUNCALF DAVID JOHN;RANNARD STEVEN PAUL;LONG JAMES;WANG DONG;ELPHICK ANDREW JAMES;STANIFORTH JOHN;CHAUVIN DANIELE;FOSTER ALISON JAYNE |
发明人 |
DUNCALF DAVID JOHN;RANNARD STEVEN PAUL;LONG JAMES;WANG DONG;ELPHICK ANDREW JAMES;STANIFORTH JOHN;CHAUVIN DANIELE;FOSTER ALISON JAYNE |
分类号 |
A61K31/439;A61P1/00;A61P29/00 |
主分类号 |
A61K31/439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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