发明名称 Substituted biphenyl carboxylic acids and derivatives thereof
摘要 <p>The present invention relates to compounds having the general formula (I) with the definitions of X,Y and A given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of ³-secretase activity. wherein A is O, NH, S; X is a bond or a group -CR 5 R 6 Y is a carboxy group -C(O)OH or a substituted or unsubstituted tetrazole group; and/or a salt or ester thereof.</p>
申请公布号 SI1849762(T1) 申请公布日期 2009.12.31
申请号 SI20060030391T 申请日期 2006.04.21
申请人 CELLZOME LIMITED 发明人 WILSON FRANCIS;REID ALISON;READER VALERIE;HARRISON RICHARD JOHN;SUNOSE MIHIRO;HERNANDEZ-PERNI REMEDIOS;MAJOR JEREMY;BOUSSARD CYRILLE;SMELT KATHRYN;TAYLOR JESS;LE FORMAL ADELINE;CANSFIELD ANDREW;BURCKHARDT SVENJA
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