| 摘要 |
An object of the present invention is to provide a method for producing bioactive composites having imparted thereto bioactivity, to thereby form and grow in vivo or in vitro a coating layer containing a calcium phosphate compound as the major component with a high adhesion strength on the surface of various types of porous substrates such as a porous shaped body comprising an organic polymer. The means for solving the problem is characterized by comprising at least (1) a step of immersing a porous substrate in a solution containing at least calcium ions and hydrogenphosphate ions, thereby distributing the solution to the inside of at least a part of the pores of the substrate, and (2) a step of depositing fine particles containing a calcium phosphate compound as the major component inside the pores into which the solution is introduced.
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