发明名称 HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE
摘要 To provide a novel compound which has S1P receptor agonistic activity, exhibits excellent immunosuppressing effect, gives less adverse side effects, and can be orally administered. The invention provides a compound represented by general formula (I) (wherein A is a single bond, -O-, or -CH2-; R1 represents a hydrogen atom or a C1-C6 alkyl group, and V represents any one group selected from among the following groups (1) to (3): (1) -G1-, (2) -G2-N(R2)-G3-, and (3) a group represented by formula 2, wherein each of Z1 and Z2 represents a hydrogen atom or a C1-C6 alkyl group, Z3 represents a hydrogen or the like, Q represents -CH2-O- or the like, and Y represents a group represented by formula 3, a salt thereof, or a solvate thereof.
申请公布号 US2009324581(A1) 申请公布日期 2009.12.31
申请号 US20070299483 申请日期 2007.05.09
申请人 DAIICHI SANKYO COMPANY LIMITED 发明人 MACHINAGA NOBUO;YOSHINO TOSHIHARU;CHIBA JUN;WATANABE JUN;SUZUKI TAKASHI;KIMURA YOUICHI
分类号 A61K39/395;A61K31/397;A61K31/405;A61K31/4709;A61K31/538;C07D409/12;C07D409/14;C07D413/12 主分类号 A61K39/395
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