发明名称 |
FOAMY VIRAL ENVELOPE GENES |
摘要 |
The present invention concerns the technical field of nucleic acids and expression-optimized nucleic acids. The present invention concerns especially nucleic acids comprising a mutated foamy viral envelope gene encoding a foamy viral envelope polypeptide, which comprises a leader peptide (LP), a surface unit (SU) and a transmembrane domain (TM). The present invention also relates to modified polypeptides encoded by these nucleic acids. Furthermore, the present invention regards a method for preparing pseudotyped vector particles as well as a method for treating a genetic disorder comprising administering a nucleic acid or a polypeptide encoded by that nucleic acid.
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申请公布号 |
US2009325870(A1) |
申请公布日期 |
2009.12.31 |
申请号 |
US20080147947 |
申请日期 |
2008.06.27 |
申请人 |
VECTORIA FORSCHUNGSFOERDERUNGS VEREIN E.V., C/O INSTITUT FUR VIROLOGIE UND IMMUNBIOLOGIE |
发明人 |
LINDEMANN DIRK;STIRNNAGEL KRISTIN;LUEFTENEGGER DANIEL |
分类号 |
A61K38/16;A61K31/7088;C07K14/00;C12N15/00;C12N15/11;C12P19/34 |
主分类号 |
A61K38/16 |
代理机构 |
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地址 |
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