| 发明名称 |
COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF OLIGONUCLEOTIDES |
| 摘要 |
The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes.
|
| 申请公布号 |
US2009326045(A1) |
申请公布日期 |
2009.12.31 |
| 申请号 |
US20090545778 |
申请日期 |
2009.08.21 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MEHTA RAHUL C.;HARDEE GREGORY E.;COOK PHILLIP DAN;ECKER DAVID J.;TSAI YALI JENNIFER;TEMPLIN MICHAEL V. |
| 分类号 |
A61K31/7088;C12N15/09;A61K9/107;A61K31/7125;A61K47/12;A61K47/24;A61K47/38;A61K48/00;A61P35/00;C07H21/04;C12Q1/68 |
主分类号 |
A61K31/7088 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
