ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6, 11-BICYCLOLIDES
摘要
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit superior antibacterial properties, particularly against Haemophilus influenzae. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
申请公布号
WO2009137737(A3)
申请公布日期
2009.12.30
申请号
WO2009US43225
申请日期
2009.05.08
申请人
ENANTA PHARMACEUTICALS, INC.;IYENGAR, RAJESH;WANG, YANCHUN;PHAN, LY, TAM;OR, YAT, SUN
发明人
IYENGAR, RAJESH;WANG, YANCHUN;PHAN, LY, TAM;OR, YAT, SUN