| 摘要 |
A compound having the structure (I) wherein R is an angiotensin receptor blocking group Y is -(CR1R20)1-7R5, or - C(O)(CR1R20)1-7R5; R1 and R20 are independently selected from the group consisting of hydrogen or C1-4 alkyl; R5 is -O-N=N(O)-NR3R4; and R3 and R4 are independently selected from the group consisting of CH2CH2OH, -CH2CH2OCH3, -C1-4 alkyl, unsubstituted or substituted C1-6 alkenyl, unsubstituted or substituted morpholino, amino, unsubstituted or substituted benzyl, unsubstituted or substituted phenyl, unsubstituted or substituted arylC1-4 alkyl, or R3 and R4 together with the nitrogen atom to which they are attached, form a ring selected from the group consisting of (II); or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt of the stereoisomer thereof, which is useful for treating hypertension. |
