发明名称 |
Method for producing intermediates for the production of novel macrocycles that are inhibitors of the proteasomic degradation of p27, such as argyrin and derivatives thereof, and uses of said macrocycles |
摘要 |
The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof, for a treatment in a variety of conditions, such as the induction of immunotolerance, autoimmune diseases, bacterial infections, and proliferative diseases, such as cancers. |
申请公布号 |
EP2138507(A1) |
申请公布日期 |
2009.12.30 |
申请号 |
EP20080011346 |
申请日期 |
2008.06.23 |
申请人 |
HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH;MEDIZINISCHE HOCHSCHULE HANNOVER;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER |
发明人 |
KALESSE, MARKUS;MALEK, NISAR;FRANK, ROLAND;BRODMANN, TOBIAS;BUELOW, LEILA;RENTSCH, ANDREAS;GIRBIG, ANNA-KATHARINA;EGGERT, ULRIKE |
分类号 |
C07K7/56;A61K38/04 |
主分类号 |
C07K7/56 |
代理机构 |
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代理人 |
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地址 |
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