SELF ASSEMBLED FILMS FOR PROTEIN AND DRUG DELIVERY APPLICATIONS
摘要
Provided are systems for controlled release of proteins from decomposable thin films constructed by layer-by-layer deposition. Such films generally comprise alternating layers of polymers and proteins, and may further comprise additional layers of polyions. In some embodiments, decomposable thin films and methods of using such films allow proteins to be released over an extended period of time and/or retention of as much as 100% of function of released protein.
申请公布号
WO2008157372(A3)
申请公布日期
2009.12.30
申请号
WO2008US66948
申请日期
2008.06.13
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;HAMMOND, PAULA, T.;MACDONALD, MARA, L.