发明名称 |
POLYMER/METAL COMPLEX COMPOSITE HAVING MRI CONTRAST ABILITY AND MRI CONTRASTING AND/OR ANTITUMOR COMPOSITION USING THE SAME |
摘要 |
Provided is a polymer/metal complex composite which comprises a block copolymer capable of serving as a constituent of a polymer micelle and a metal complex having an MRI contrast ability, accumulates tumor-specifically, achieves a high contrast resolution even in a small amount, and has reduced side effects and a long retention time in blood. A polymer/metal complex composite comprising a block copolymer (A) represented by general formula (a) and a metal complex (B) having an MRI contrast ability, which has a structure wherein carboxyl anions of poly(carbo) in the copolymer (A) are bonded to the metal complex (B) via metal atoms (M). |
申请公布号 |
WO2009157561(A1) |
申请公布日期 |
2009.12.30 |
申请号 |
WO2009JP61772 |
申请日期 |
2009.06.26 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY;KATAOKA KAZUNORI;KAIDA SACHIKO;CABRAL HORACIO;KUMAGAI MICHIAKI;SEKINO MASAKI |
发明人 |
KATAOKA KAZUNORI;KAIDA SACHIKO;CABRAL HORACIO;KUMAGAI MICHIAKI;SEKINO MASAKI |
分类号 |
C08G81/00;A61K9/107;A61K33/24;A61K47/34;A61K49/00;A61P35/00 |
主分类号 |
C08G81/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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