发明名称 POLYMER/METAL COMPLEX COMPOSITE HAVING MRI CONTRAST ABILITY AND MRI CONTRASTING AND/OR ANTITUMOR COMPOSITION USING THE SAME
摘要 Provided is a polymer/metal complex composite which comprises a block copolymer capable of serving as a constituent of a polymer micelle and a metal complex having an MRI contrast ability, accumulates tumor-specifically, achieves a high contrast resolution even in a small amount, and has reduced side effects and a long retention time in blood. A polymer/metal complex composite comprising a block copolymer (A) represented by general formula (a) and a metal complex (B) having an MRI contrast ability, which has a structure wherein carboxyl anions of poly(carbo) in the copolymer (A) are bonded to the metal complex (B) via metal atoms (M).
申请公布号 WO2009157561(A1) 申请公布日期 2009.12.30
申请号 WO2009JP61772 申请日期 2009.06.26
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY;KATAOKA KAZUNORI;KAIDA SACHIKO;CABRAL HORACIO;KUMAGAI MICHIAKI;SEKINO MASAKI 发明人 KATAOKA KAZUNORI;KAIDA SACHIKO;CABRAL HORACIO;KUMAGAI MICHIAKI;SEKINO MASAKI
分类号 C08G81/00;A61K9/107;A61K33/24;A61K47/34;A61K49/00;A61P35/00 主分类号 C08G81/00
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