ENRICHED PLANT EXTRACT, COMPOUND, AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

摘要

The present invention relates to an enriched plant extract containing a mixture of two compounds, obtained from the leaves of the plant Vitex negundo, used for the treatment of proliferative disorders such as cancer. The invention also relates to a compound of formula (1) : The compound of formula (1) can be isolated from the enriched extract and has antiproliferative activity. The present invention further relates to a herbal composition including enriched extract of leaves of Vitex negundo containing the mixture of two compounds as main ingredient for the treatment of proliferative disorders such as cancer. The invention also relates to a pharmaceutical composition including the compound of formula (1), for the treatment of proliferative disorders such as cancer. The invention further relates to the method of treatment of proliferative disorders such as cancer, by adapting the compositions in mammals, in need thereof.