MORPHOLOGICAL ANALYSIS

摘要

A method for deriving a biomarker from a structural analysis of medical images is described, including the calculation of pairwise, between-subject, measures of similarity and transformation of the pairwise measures of similarity into a subject specific biomarker. In one example, the biomarker is based on volume or shape comparisons of labelled and segmented anatomical structures in brain images from the subject and two or more clinical groups.