发明名称 |
Inhibitors of Akt activity |
摘要 |
The present invention is directed to compounds which contain a five-membered heterocyclic ring fused to a substituted pyridine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
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申请公布号 |
US7638530(B2) |
申请公布日期 |
2009.12.29 |
申请号 |
US20050554185 |
申请日期 |
2005.10.21 |
申请人 |
MERCK & CO., INC. |
发明人 |
BILODEAU MARK T.;WU ZHICAI |
分类号 |
A61K31/4745;A61K;A61K31/44;C07D471/02;C07D471/14;C07D471/16;C07D491/02;C07D498/02 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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