| 摘要 |
A compound of formula (I): wherein X represents O or S; R1 represents C1-6 alkyl, C3-8 cycloalkyl, C3-8 cycloalkylmethyl or C3-8 cycloalkenyl any of which optionally may be substituted by one or more methyl groups or halogen atoms or R1 represents aryl, substituted aryl, heteroaryl or substituted heteroaryl; R2 represents hydrogen, methyl, which may be in either the alpha or beta configuration, or methylene; R3 and R4 are the same or different and each independently represents hydrogen, halogen or a methyl group; and <img id="CUSTOM-CHARACTER-00001" he="2.79mm" wi="4.57mm" file="US07638508-20091229-P00001.TIF" alt="custom character" img-content="character" img-format="tif"/> represents a single or a double bond; or a physiologically acceptable salt or solvate thereof, and pharmaceutical formulations and methods of use thereof.
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