发明名称 |
Fused pentacyclic polyethers |
摘要 |
Disclosed are polycyclic polyether compounds of formula I and pharmaceutical compositions comprising such compounds. wherein R, OR1, and R2 are as defined herein. Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.
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申请公布号 |
US7638500(B2) |
申请公布日期 |
2009.12.29 |
申请号 |
US20070733601 |
申请日期 |
2007.04.10 |
申请人 |
UNIVERSITY OF NORTH CAROLINA AT WILMINGTON |
发明人 |
BADEN DANIEL G.;ABRAHAM WILLIAM M.;BOURDELAIS ANDREA J.;MICHELLIZA SOPHIE |
分类号 |
A61K31/7072;A61K31/35;A61K31/353;A61K31/42;A61K31/4433;A61K31/52;C07D493/04;C07D493/14;C07D493/22;C07H19/04 |
主分类号 |
A61K31/7072 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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