ENYNE-1,6-DIOL DERIVATIVES AND SYNTHESIS OF THEM

摘要

PURPOSE: A method for manufacturing enyne-1,6-diol derivatives is provided to selectively synthesize enyne-1,6-diol derivatives by reacting an allyl indium reagent with an allenyn-1,6-diol compound through in-situ reaction without separate refining process. CONSTITUTION: A method for manufacturing enyne-1,6-diol derivatives comprises the steps of: reacting an allyl halide derivative represented by chemical formula 3 and indium to prepare an allyl indium reagent represented by chemical formula 4; and reacting an allylnyne-1,6-diol compound represented by chemical formula 2 to prepare an enyne-1,6-diol derivative represented by chemical formula 1.