PRODUCTION OF RECOMBINANT BOS TAURUS GROWTH HORMONE WITH PICHIA PASTORIS

摘要

The present invention provides the production of recombinant bovine growth hormone (rbGH) using a synthetic gene sequence and maintaining the characteristics of natural bovine growth hormone. According to the present invention, is used a synthetic gene sequence that uses preferential codons and optimized content of nucleotide GC bases for P. pastoris. The present process enables the production of this hormone on a large scale and with high efficiency expression.