| 发明名称 |
INDOLE AND INDOLINE CYCLOPROPYL AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS |
| 摘要 |
The invention is directed to indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.
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| 申请公布号 |
US2009318518(A1) |
申请公布日期 |
2009.12.24 |
| 申请号 |
US20080527736 |
申请日期 |
2008.02.22 |
| 申请人 |
BOYD MICHAEL;COLUCCI JOHN;HAN YONGXIN |
发明人 |
BOYD MICHAEL;COLUCCI JOHN;HAN YONGXIN |
| 分类号 |
A61K31/41;A61K31/404;C07D209/42;C07D403/12 |
主分类号 |
A61K31/41 |
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