| 发明名称 |
Thiazoles and oxazoles useful as modulators of ATP-binding cassette transporters |
| 摘要 |
Disclosed are compounds of formula (I), wherein the substituents are as defined in the specification. The compounds are modulators of ABC transporter activity and anion channels, and are useful in the treatment of diseases such as cystic fibrosis.
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| 申请公布号 |
NZ547220(A) |
申请公布日期 |
2009.12.24 |
| 申请号 |
NZ20040547220 |
申请日期 |
2004.11.15 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
HADIDA RUAH, SARAH S;MILLER, MARK T;GROOTENHUIS, PETER D J;HAMILTON, MATTHEW |
| 分类号 |
A61K31/42;A61K31/422;A61K31/426;A61K31/427;C07D263/34;C07D277/56;C07D417/04;C07D417/06;C07D417/12 |
主分类号 |
A61K31/42 |
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