发明名称 |
AUTOPHILIC ANTIBODIES AND METHOD OF MAKING THE SAME |
摘要 |
Antibodies having noncovalent, autophilic properties are disclosed. The autophilic antibodies are derived from antibodies conjugated with an autophilic peptide. Such autophilic antibodies can promote apoptosis of target cells and enhance therapeutic efficacies in the treatment of patients with diseases or disorders responsive to antibody therapy. Compositions containing the antibodies, and methods of making and using the antibodies are also disclosed.
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申请公布号 |
US2009317379(A1) |
申请公布日期 |
2009.12.24 |
申请号 |
US20090481248 |
申请日期 |
2009.06.09 |
申请人 |
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发明人 |
KOHLER HEINZ;MULLER SYBILLE;MORGAN, JR. ALTON CHARLES |
分类号 |
A61K39/395;A61K47/48;C07K1/00;C07K7/08;C07K14/00;C07K16/28;C07K16/30;C07K16/32;C07K16/40;C07K16/46;C07K19/00;G01N33/53;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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