Method for producing 4-pentafluoride-sulfanyl-benzoylguanidines that are NHE1 inhibitors

摘要

The disclosure relates to a process for the preparation of 4-pentafluoride-sulfanyl-benzoylguanidines of formula (I) wherein groups from R1 to R4 correspond to meanings given in the specification. The compounds of the formula (I) are sodium-hydrogen-exchanger type 1 (NHE1) inhibitors and can be used for curing cardiovascular diseases.