摘要 |
Disclosed is a non-surgical method for causing necrosis of skin on a sheep, at selected anatomical locations, said method comprising administration to the skin of such locations, an effective amount of an anionic surfactant (such as an alkyl sulphate, an alkyl benzene sulphonate, or an alkylether sulphate) capable of causing skin necrosis. Particularly preferred anionic surfactants are sodium tetradecyl sulphate, sodium decyl sulphate, sodium lauryl sulphate, sodium myristyl sulphate and sodium cetyl sulphate. In addition to the above method, it is also disclosed that the anionic surfactant can be mixed with an antifibrinolytic agent that enhances skin necrosis (such as aminocaproic acid and tranexamic acid).
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