Method for Reconstructing Protein Database and a Method for Identifying Proteins by Using the Same Method

摘要

The present invention relates to a method for reconstructing protein database for identifying a protein and a method for screening a protein using the same, more precisely a method for reconstructing protein database comprising the steps of i) Grouping proteins having a required homology by using the clustering software from the primary database which minimizes the overlapping of proteins and then recording sequence information of each protein group on a recording system of a computer; and ii) Designating a representative protein in each protein group and then constructing the representative protein database composed of the representative proteins, followed by recording the results containing sequence information on a recording system of a computer, and a method for identifying a protein using the same; and iii) Identifying proteins from the protein sequences of the protein group which the identified representative protein belongs to. The method for reconstructing protein database and the method for identifying the protein of the invention are very useful for the investigation of endogenous proteins and their functions and interactions, and are further effectively used for the development of diagnostic and therapeutic agents for various diseases.