Methods and means for diagnostics, prevention and treatment of Mycobacterium infections and tuberculosis disease

摘要

Provided is the use of a source of one or more specified polypeptides of Mycobacterium tuberculosis dormancy (DosR) regulon sequences and analogues, homologues or functional fragments thereof, in the manufacture of a medicament for inducing an immune response against Mycobacterium infection in a human. Further provided are corresponding compositions for immunization against Mycobacterium infections and methods of diagnosis using said compositions.