发明名称 |
Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
摘要 |
The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
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申请公布号 |
US2009317420(A1) |
申请公布日期 |
2009.12.24 |
申请号 |
US20050658842 |
申请日期 |
2005.07.29 |
申请人 |
CHIRON CORPORATION |
发明人 |
TELFORD JOHN;GRANDI GUIDO;LAUER PETER;MORA MARLROSA;MARGARIT Y ROS IMMACULADA;MALONE DOMENICO;BENSI GUILIANO;RINAUDO DANIELA;MASIGNANI VEGA;BAROCCHI MICHELLE;RAPPULOI RINO |
分类号 |
A61K39/085;A61P31/04;C07K14/315;C12N1/20;C12P21/02 |
主分类号 |
A61K39/085 |
代理机构 |
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地址 |
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