IMPROVED VACCINES AGAINST BORDETELLA PERTUSSIS BASED ON LPS GLYCOSYLTRANSFERASE MUTANTS
摘要
<p>The invention relates to an improved vaccine against pertussis wherein mutants of Bordetella pertussis having a modified LPS molecule or the obtainable LPS molecules are used. These mutants or the obtainable LPS molecules may further be used as an adjuvant.</p>
申请公布号
EP2134743(A2)
申请公布日期
2009.12.23
申请号
EP20080723920
申请日期
2008.03.25
申请人
DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS
发明人
GEURTSEN, JEROEN JOHANNES GERARDUS;TOMMASSEN, JOHANNES PETRUS MARIA;VAN DER LEY, PETER ANDRE