| 摘要 |
The present invention provides 5,6;8,9-tetrahydro-7H-dibenz(d,f)azonine derivatives of the formula: <IMAGE> wherein R1 and R2, which are the same or different, are hydrogen or halogen atoms or lower alkyl or alkoxy radicals, R3 is a hydrogen atom or a lower alkyl radical, R4 is a hydrogen atom or a lower alkyl or alkanoyl radical and n is 1 or 2; and the pharmaceutically acceptable salts thereof formed with inorganic and organic acids; but excluding 6-benzyl-2,12-dimethoxy-1-hydroxy-7-methyl-5,6;8,9-tetrahydro-7H-diben z(d,f)azonine in which case R1, R2 and R4 are hydrogen, n is 1 and R3 is methyl. The lower alkyl, alkanoyl and alkoxy radicals are straight chained or branched radicals containing 1 to 5 carbon atoms. The present invention also provides a process for the preparation of these compounds, as well as pharmaceutical compositions containing them. |
