SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY ON THE INFLAMMATORY RESPONSE
摘要
The present invention relates to novel synthetic analogues of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.
申请公布号
WO2009153434(A2)
申请公布日期
2009.12.23
申请号
WO2009FR00595
申请日期
2009.05.20
申请人
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS;UNIVERSITE D'ORLEANS;QUESNIAUX FYFFEL, VALERIE;MARTIN, OLIVIER;FRONT, SOPHIE
发明人
QUESNIAUX FYFFEL, VALERIE;MARTIN, OLIVIER;FRONT, SOPHIE