发明名称 |
Ligand |
摘要 |
The invention relates to a multivalent ligand comprising non-complementary binding domains specific for the same epitope, wherein the epitope is comprised by a target antigen having multiple copies of said epitope, wherein each epitope binding domain is an immunoglobulin single variable domain or wherein each epitope binding domain comprises a non-immunoglobulin protein scaffold. The invention relates also to a ligand which binds a multisubunit target antigen. |
申请公布号 |
EP2135879(A2) |
申请公布日期 |
2009.12.23 |
申请号 |
EP20090158112 |
申请日期 |
2003.06.30 |
申请人 |
DOMANTIS LIMITED |
发明人 |
WINTER, GREG;TOMLINSON, IAN;IGNATOVICH, OLGA;HOLT, LUCY;DE ANGELIS, ELENA;JONES, PHILIP |
分类号 |
C07K16/46;C07K16/00;C07K16/18;C07K16/24;C07K16/28;C07K16/40;C07K16/42;C12N5/10;C12N15/13;C12N15/79;G01N33/542;G01N33/577;G01N33/68 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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