PHARMACEUTICAL COMPOSITIONS OF DEXIBUPROFEN

摘要

The present invention relates to formulations of pharmaceutical compositions and in particular to a process of manufacture of such pharmaceutical compositions comprising dexibuprofen and/or salts in oral dosage form possessing high in-vitro dissolution and enhanced bioavailability in humans. Importantly, the invention is directed to high in-vitro dissolution of a poor water soluble drug dexibuprofen by controlling the particle size of the active ingredient of the invention such as dexibuprofen, to enable a significant improvement in the in-vivo performance of the active ingredient.