The present disclosure relates to immunoglobulins with reduced aggregation and compositions, methods of generating such immunoglobulins with computational tools and methods of using such immunoglobulins particularly in the treatment and prevention of disease.
申请公布号
WO2009155513(A2)
申请公布日期
2009.12.23
申请号
WO2009US47948
申请日期
2009.06.19
申请人
NOVARTIS AG;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;CHENNAMSETTY, NARESH;HELK, BERNHARD;KAYSER, VEYSEL;TROUT, BERNHARDT;VOYNOV, VLADIMIR
发明人
CHENNAMSETTY, NARESH;HELK, BERNHARD;KAYSER, VEYSEL;TROUT, BERNHARDT;VOYNOV, VLADIMIR